Tisssue factor and factor viia cross-species compatibility Tisssue factor and factor viia cross-species compatibility
نویسندگان
چکیده
1. Astract 2. Introduction 3. TF and FVIIa 3.1. Purification, cloning and expression of TF 3.2. TF structure and function 3.3. Purification, cloning and expression of FVII 3.4. FVIIa structure and function 3.5. Interaction of FVIIa with TF 3.6. Binding of human FVIIa to sTF, lipidated TF and cell surface TF 3.6.1. FVIIa binding to sTF 3.6.2. FVIIa binding to lipidated TF and to cell surface TF 3.7. Effect of FFR-FVIIai on PT in human plasma and plasmas from other species 3.8. Species compatibility with TF-FVIIa substrates, FX, FIX, and PARs 4. Selected human-animal cross-species TF and FVII compatibilities 4.1. Bovine TF and FVIIa 4.2. Canine TF and FVIIa 4.3. Rabbit TF and FVIIa 4.4. Murine TF and FVIIa 4.5. Rat TF and FVIIa 4.6. Zebrafish TF and FVIIa 5. Perspectives 6. Acknowledgement 7. References
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